Pesquisa sobre: RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2 
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Descritor Inglês:   Receptor, Fibroblast Growth Factor, Type 2 
Descritor Espanhol:   Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos 
Descritor Português:   Receptor Tipo 2 de Fator de Crescimento de Fibroblastos 
Sinônimos Inglês:   Fibroblast Growth Factor Receptor 2  
Categoria:   D08.811.913.696.620.682.725.400.178
D12.776.543.750.060.441
D12.776.543.750.750.400.370.750
Definição Inglês:   A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME). 
Relacionados Inglês:   Acrocephalosyndactylia
Antley-Bixler Syndrome Phenotype
Craniofacial Dysostosis
 
Nota Histórica Inglês:   2006(1999) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   50734 
Identificador Único:   D051497 

Ocorrência na BVS:
 

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